GLP-2T is a structurally complex, 39-amino-acid synthetic peptide engineered to explore advanced multi-pathway metabolic regulation. It represents a major breakthrough in incretin biology as a first-in-class, dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.
In cellular and in vitro models, GLP-2T is extensively researched for its synergistic “twincretin” mechanism. By targeting both GIP and GLP-1 receptors simultaneously, this peptide provides researchers with a novel tool to investigate enhanced insulin sensitivity, glucose-dependent insulin secretion, and localized tissue metabolic pathways. Additionally, its unique molecular structure features a C20 fatty diacid moiety that allows researchers to observe sustained homeostatic activity and prolonged structural stability during experimental assays.
Core Research Areas
Dual Incretin Activation: Simultaneously targets GIP and GLP-1 receptor pathways to study additive metabolic signaling and glycemic control.
Insulin Secretion Dynamics: Investigated for its ability to enhance first- and second-phase insulin secretion under elevated glucose conditions.
Metabolic Rate and Adiposity: Researched for its localized effects on delaying gastric motility and modulating nutrient absorption pathways in tissue models.
Storage & Handling
Lyophilized: Stable at room temp for up to 3 weeks. Store long-term desiccated below -18°C.
Laboratory Research Disclaimer: This product is synthesized and distributed exclusively for laboratory research use and in vitro testing. It is not approved for human consumption, therapeutic use, or clinical application.
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