MOTS-c is a structurally unique 16-amino-acid peptide encoded directly within the mitochondrial genome. Functioning as an autonomous signaling molecule, it plays a central role in systemic metabolic regulation, cellular energy balance, and longevity pathways.
Often researched as an “exercise mimetic,” MOTS-c targets skeletal muscle tissue to upregulate glucose clearance and enhance fatty acid oxidation. By activating the AMPK signaling pathway, this novel peptide maintains cellular homeostasis under metabolic stress, making it a premier compound in contemporary anti-aging and metabolic research.
Core Research Areas
Metabolic Flexibility: Enhances insulin sensitivity and glucose flux in muscle tissue.
Mitochondrial Biogenesis: Activates the AMPK pathway to stimulate cellular energy production.
Longevity & Muscle Retention: Researched for its role in mitigating age-related physical decline.
Storage & Handling
Lyophilized: Stable at room temp for up to 3 weeks. Store long-term desiccated below -18°C.
Laboratory Research Disclaimer: This product is synthesized and distributed exclusively for laboratory research use and in vitro testing. It is not approved for human consumption, therapeutic use, or clinical application.







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