Melanotan-2 is a synthetic, cyclized 7-amino-acid peptide designed to mimic natural alpha-melanocyte-stimulating hormone (alpha-MSH). It features a unique circular molecular structure that makes it significantly more potent and metabolically stable in testing environments compared to linear peptides like Melanotan-1.
In laboratory research, Melanotan-2 is used to study cellular pigmentation pathways and systemic receptor behaviors. Because its compact design allows it to cross the blood-brain barrier effectively, researchers utilize it to investigate non-selective binding across multiple melanocortin receptors (MC1R, MC3R, MC4R, and MC5R). This multi-receptor interaction makes it a key compound for studying not only melanin production (melanogenesis) but also central nervous system pathways regulating metabolic rate, appetite suppression, and sexual function models.
Core Research Areas
Accelerated Melanogenesis: Researched for its capacity to stimulate rapid melanin production in cellular models to study UV defense mechanisms.
Central Appetite Modulation: Investigated for its interaction with MC4R receptors in the brain to observe its effects on satiety and energy expenditure.
Systemic Receptor Signaling: Studied to understand the broad-spectrum behavioral and physiological impacts of activating multiple melanocortin receptor paths simultaneously.
Storage & Handling
Lyophilized: Stable at room temp for up to 3 weeks. Store long-term desiccated below -18°C.
Laboratory Research Disclaimer: This product is synthesized and distributed exclusively for laboratory research use and in vitro testing. It is not approved for human consumption, therapeutic use, or clinical application.







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